A while back I wrote on the browser becoming the OS of tomorrow. Well, with the new version of FF3.5 with HTML5 built in we are getting closer to than ever before. This technology is the genesis of making 3rd party extensions such as Adobe Flash and MS Silverlight obsolete in the way of making audio/video accessible native in the browser framework.
As always, we as users are the recipients of this goodness that is manifested out of the competition between MS IE, Safari, Chrome, FF, and Opera. They are all market leaders in their respective technologies and are bringing us closer to the Web as a true cloud service.
We are not in the era of Software-as-a-Service but Service-as-a-Service. When Twitter, FB, and other platforms are being accessed via phones, netbooks, PC's, Mac's, etc. these services are all hardware and religion agnostic. They just run in the browser or are presented in wrappers that interface with it.
Since the cloud is the new mainframe we should expect more applications to run within the framework of the browser, and more computers to simply become portals.